Human med nis

Human med nis. These factors include your dog's overall health, other The present study explored the combined cytotoxic effects of adenovirus-mediated CD and NIS under the control of the progression elevated gene-3 (PEG-3) promoter (Ad-PEG-3-CD-NIS) with Na 131 I/5-FC against the human thyroid cancer TT cell line in vitro. Zavodu za zdravstvenu zaštitu Aleksinac od 1994 do 1995 Lekar opšte medicine. The organ of copulation and urination in the male; formed of three columns of erectile tissue, two arranged laterally on the dorsum (corpora cavernosa penis) and one median ventrally (corpus spongiosum penis); the urethra traverses the latter; the extremity (glans penis) is formed by an expansion of the corpus spongiosum and is more or less completely covered by a free fold of skin (prepuce). Mesto: 18000 Niš. In an era where medical knowledge is growing exponentially and is constantly evolving, it is crucial to stay up to date. The average adult human brain only weighs about 3 pounds, so most of the weigh Donating your unwanted furniture to Habitat for Humanity is a great way to give back to your community and help those in need. Osteoarthritis and fibromyalgia can also ca “Human wants” are those things that people desire to have above what they truly need in order to live. Unlike conventional liposuction methods, during the water-jet assisted liposuction (WAL) and the water-jet assisted fat transfer, the fat is gently detached from the tissue structure by means of a flat, fan-shaped water-jet and may be aspirated at the same time. . Kontaktirajte nas -. Kliničkih pregleda: interniste, psihijatra, neuropsiohijatra, oftalmologa; Obuke prve pomoći; Ultrazvučnu dijagnostiku; Psihološko savetovanje (bračno, roditeljsko, razvojno) Phone: +44 113 295 1132. Innovation. Get phone number, address, Geo-location, website, email, working hours and more details about it. Aug 28, 2021 · Dermatologija Human MED ‍⚕️ 栗‍♀️ Telefon za zakazivanje pregleda kod Dr Marine Đorđević: 018 300 615 018 300 616 060 230 20 54 060 230 20 55 Ukoliko Vam se dopala objava, sačuvajte je i OBJECTIVE To examine the possibility of human sodium iodide symporter (hNIS) protein expression in lung cancer cells. Ako imate bilo kakva pitanja ili želite da zakažete pregled, naš tim je spreman da vas sasluša i pruži podršku. As individuals and organizations strive to make a positive impact on society, the con Human values are the principles, convictions and internal beliefs that people adopt and follow in their daily activities. Zavod za zdravstvenu zaštitu radnika Human Med is a Medical Center located in - Niš, Serbia. That is about 8 percent of the weight of a human body. 25 inches, and the average for women is . Using the body-jet ®, liposuction and lipotransfer is performed in a safe, effective and easy way. We applied a scenario-based evaluation technique in order to understand the barriers and facilitators to nurse use of the NIS as part of improving the healthcare delivery system. 8%) were recorded for the first time in the Eastern Mediterranean basin (i. 2024. The shaft is the longest part of it. Poliklinika Humano, Bulevar dr Zorana Đinđića 15, Niš. Although the measurement is often reserved for appliances and machines, it can also be applied the energy taken in and given off by each hum The Humane Society is a non-profit organization that works to protect animals from cruelty and neglect. Jan 1, 2015 · To generate a more efficient in vivo reporter and therapeutic gene, we optimized the coding sequence of the human sodium/iodide symporter (NIS) gene by replacing NIS DNA codons from wild type to new codons having the highest usage in human gene translation. Products that eliminate flea infestations, such as food-grade diatomaceous earth, can be The five types of human behavior, according to My PTSD are passive-aggressive, assertive, aggressive, passive and the lesser-known alternator, a pattern of behavior where an indivi BTUs are a way that energy is measured. Sistematski pregledi Sistemaski pregledi - činjenice : Studije u zemljama koje ozbiljno investiraju u prevetivu i sistematske preglede pokazuju da ljudi koji polažu na prevetivu i sistematske preglede imaju: Specijalizovana medicinska ustanova za internu medicinu, pedijatriju, neuropsihijatriju, opštu hirurgiju i radiologiju. Qualität. These institutions are known for their rigorous academic programs, exc Chicago Med is a popular medical drama television series that has captivated audiences with its intense storylines, compelling characters, and realistic portrayal of the medical fi Penn Med Radnor is a premier healthcare facility that has been providing exceptional cardiovascular care to its patients for many years. Stephan Aldinger. godine ima Akreditaciju u domenu biohemijske, mikrobiološke i patohistološke laboratorije. Klinika za urologiju, Kilinički centar Niš od 2003 Sep 7, 2023 · Methods: In this study, to noninvasively assess transplanted cell engraftment, human SLC5A5, which encodes a sodium/iodide symporter (NIS) that transports radioactive tracers such as 125 I, 18 F-tetrafluoroborate (TFB), and 99m Tc-pertechnetate (99m TcO 4-), was transduced into human induced pluripotent stem cells (iPSCs), and nuclear medicine Human Med AG – Premium water-jet technology humanmed 2023-11-07T08:54:32+01:00. Dec 14, 2022 · Rat NIS shares 89% sequence identity with human NIS (Supplementary Fig. May 17, 2024 · Anatomy of a Penis. Hematologija i koagulacija Biohemija i imunohemija Imunologija i alergologija Mikrobiologija i virusologija Patohistologija i citologija Genetika i imunogenetika Feb 2, 2017 · NIS staining has been reported in human placental endometrial glands during the first trimester of pregnancy . Pregled dojki. Kralja Stefana Prvovenčanog 183/2, Vranje Poliklinika Human Vam pruža kompletnu zdravstvenu uslugu na jednom mestu praćenu najsavremenijom dijagnostikom i pristupom lečenja. Human DNA and canine DNA are so vastly different that pregnancy be The large and small intestines of the average adult human, when stretched, are only an average of 25 feet long and cannot stretch around the world. Interestingly, PDS mRNA levels in breast cancer tissue seem to be influenced by the estrogen receptor status and age of the patients, while NIS mRNA levels were ZZZZR Human Med Vojvode Tankosića 9, Niš ☎️ 018 300 615 060 230 20 54 Jan 3, 2024 · Penis infections: Many infections can affect the penis and cause painful symptoms such as redness, swelling, and itching. Bulevar dr Zorana Đinđića 14-24, 18000 Niš (Medijana) 018/538-889 Poliklinika Human, Nis. 2) and has similar transport properties 6,12,13,14. METHODS Human lung A549 cancer cells were thawed and cultured in vitro. The location of Flea bites on humans can be both uncomfortable and itchy, but they can also be dangerous if left untreated. Poliklinika Human Vam nudi mogućnost da na jednom mestu uz pomoć najsavremenijih dijagnostičkih metoda i aparata, kompletne laboratorijske analize svih parametra i vrhunskog tima stručnjaka radiologa, hirurga i onkologa, dobijete potpunu sliku stanja Vaše dojke i obezbedite sebi adekvatnu terapiju i lečenje u pravo vreme. Coordinate: 53. The focus of the humanities is on huma The thickness of the average human skull depends on a number of factors, including gender. Humans are warm-blooded mammals, which do not lay eggs. Paramecia have even been Human beings belong to the primate order, which is in the mammalia class. Zavod za zdravstvenu zaštitu radnika Human Med se nalazi u Nišu i pruža usluge: Izadavanja lekarskih uverenja za zaposlene, vozače, decu, studente i dr. Telefoni: + 381(0)18 538 889 + 381(0)60 Urologija je grana kliničke medicine koja se bavi uzrocima, razvojem i dijagnostikom oboljenja urinarnog trakta kod muškaraca i kod žena, kao i reproduktivnim organima kod muškaraca. Misirlis-Proffesor,Department of Mechanical Engineering and Aeronautics,University of Patras The Schwerin-based manufacturer of medical products, Human Med AG, has a new managing director: Dr. Several groups have investigated the significant potential of the NIS gene to induce radioiodine accumulation across various tumor types. Citations may include links to full text content from PubMed Central and publisher web sites. Niš, Centralna Srbija, Serbia Medical Representative Delta Naissa Jul In human anatomy, the penis (/ ˈ p iː n ɪ s /; pl. Lawn and garden stores, such as Tractor Supply Co If you’re considering investing in a human hairpiece, it’s important to understand the different types available on the market. Korisnicma su dostupni pregledi specijalista, lab i radiološka dijagnostika. Izadavanja lekarskih uverenja za zaposlene, vozače, decu, studente i dr. Phone: +49 (0)385 395 70 0; Fax: +49 (0)385 395 70 29; Mail: info [at] humanmed. Premium Wasserstrahl-Technologie. 8020981, -1. Poliklinika Human osnovana je 2007 godine u Nisu. They are dedicated to providing care and protection for animals in need, as Humans are the only animals to have invented computers, and no animal uses them in nature. Po svojoj suštini i Zakazivanje obuke iz Prve Pomoći na telefone: 018 300 615 018 300 616 060 230 20 54 060 230 20 55 ZZZZR Human Med, Vojvode Tankosića 9, Niš Poliklinika Human - 20. Jan 16, 2023 · Purpose Sodium iodide symporter (NIS), as a broadly exploited cancer theranostic molecule, has attracted considerable interest in non-thyroidal tumors. Endoskopija. Some examples of human qualities include the ability to ask questions, human DNA and a spoken language. Whether you’re looking to declutter your home or just If you’ve ever heard someone say that they are studying humanities, you may have found yourself wondering exactly what that means. In this review, we discuss the role of NIS as a theranostic gene in pre-clinical extra-thyroidal cancer NANETS2022 15th Annual Multidisciplinary NET Medical Symposium NANETS 2022 Trials In Progress (10 abstracts) Phase 1-2 Trial of Vesicular Stomatitis Virus Expressing Human Interferon-β and NIS (VSV-IFNβ-NIS), with Pembrolizumab, in Patients with Neuroendocrine Carcinoma Медицински факултет Универзитетa у Нишу је државна, образовна и научна институција високог образовањa у Рeпублици Србиjи. The average reaction time of human beings is around . The information here serves as a valuable resource for users seeking Medical Center in Niš, Serbia, by offering comprehensive details about Zavod za zdravstvenu zaštitu radnika Human Med and its location. Ova speijalizovana ordinacija obavlja različite specijalističke preglede i ostale usluge - specijalističke i laboratorijske. Urogenitalni sistem čine organi urinarnog (bubrezi, ureteri i mokraćna bešika) i genitalnog (penis, testisi, semevodi, prostata) sistema muškarca. Building on a long history of success in the fields of general surgery, urology and neurosurgery, where gentle water-jet tissue dissection is essential, in 2004 HUMAN MED ® turned its vision to the aesthetics field. poliklinikahuman. net. , supply oxygen tank refills and systems to customers needing home oxygen therapy. 28 inche Most people are aware that primates are the closest living relatives to humans. Humane societies are organizations that work to protect animals from cruelty, neglect, and abuse. Our quality management system is certified according to EN ISO 13485. We examined the role of NIS in the uptake of the alpha-particle emitting radiohalide [(211)At]astatide in the UVW human glioma cell line transfected to express NIS. Hitna pomoć Niš od 1995 Lekar opšte medicine Klinika za urologiju, Kilinički centar Niš od 2003 Specijalizant Klinički centar Ljubljana od 2009 Usavršavanje iz urologije. Humanities cover a broad range of different studi Although other similar creatures, such as amoebas, are known to cause illness, paramecia do not live inside humans and are not known to cause any diseases. rs Poliklinika Human je vrhunska specijalizovana medicinska ustanova, registrovana kao poliklinika za oblast interne medicine, laboratorije za medicinsku biohemiju, laboratorije za mikrobiologiju i laboratorije za patohistologiju. Poliklinika Human, Poliklinika HUMAN je vrhunska specijalizovana medicinska ustanova, registrovana kao „Poliklinika za oblast interne medicine, laboratorije za medicinsku biohemiju, laboratorije za mikrobiologiju i laboratorije za patohistologiju“. 215 seconds. The cells were divided into an experimental group transfected with a recombinant pcDNA3-hNIS plasmid and a control group transfected only with a pcDNA3 plasmid. Laboratorija. Some mammals can be trained to use computers, however, and some non-human primates regula The humanities include the disciplines of history, visual and performing arts, language, music, religion, philosophy, culture and literature. Humans are part of this phylum, because they have a notochord when they are in the womb; this notochord will eventually turn into a spinal cor 0. Welcome to the official e-learning platform!School of Medicine, University of Niš, Serbia Molecular and human genetics 2023/2024. Interna medicina je grana medicine koja se fokusira na prevenciju, dijagnostiku i lečenje bolesti unutrašnjih organa kod odraslih osoba. Poliklinika Human Vam pruža kompletnu zdravstvenu uslugu na jednom mestu praćenu najsavremenijom dijagnostikom i pristupom lečenja. Urologija. ZZZZR Human Med Vojvode Tankosića 9, Niš ☎️ 018 300 615 060 230 20 54 Jul 31, 2024 · SLUŽBA MEDICINE RADA ZAVOD ZA ZDRAVSTVENU ZAŠTITU RADNIKA “HUMAN MED” Medicina rada je grana medicinske delatnosti koja se bavi stanjima i bolestima nastalim pod uticajem određenih faktora radne sredine (fizičkog, hemijskog i biološkog porekla), kojima je neka osoba profesionalno izložena obavljajući svakodnevno poslove i radne zadatke na svom radnom mestu. POLIKLINIKA HUMAN, Niš, Poliklinika Human Bulevar Dr Zorana Ðinđića 14. Other members of the primate order include gorillas, apes and lemurs. The Codon Adaptation Index (CAI), representing the number of codons effective for human Medical resident at Otorinolaringology and head and neck surgery · Experience: Poliklinika HUMAN · Education: Faculty of Medicine, University of Nis · Location: Serbia · 447 connections on LinkedIn. Instead, humans, like o If you’re an animal lover, you may be wondering how you can help out your local humane society. Interna medicina. Zavod za zdravstvenu zaštitu radnika Human Med is a popular Medical Center in the city Niš, Serbia. Preliminary studies of immune responses in patients receiving VSV-IFNβ-NIS therapy suggest some patients develop T cell responses to viral antigens and known tumor antigens. rs. com; MediGroup dom zdravlja Kalča se nalazi u Nišu, u ulici Nikole Pašića broj 28. Delatnosti: specijalistički pregled, ultrazvučna dijagnostika. Budite u sigurnim rukama. Mar 20, 2024 · Out of the 130 Indo-Pacific/Red Sea NIS fishes analyzed in our dataset, the vast majority (N = 122; 93. Poliklinika Human - Niš, Vranje. 525196. Popunite kontakt formu ispod i očekujte brz odgovor. Poliklinika Human nalazi se u Nišu. Th, Thessalonki, 2010 The importance of stem cells - stem cells differentiation, treatments and therapies Janjic Milka , Eleftherios Vavoulidis Mentor: I. The opening at the tip of the head, where urine and semen Sep 19, 2013 · The solute carrier family 5 member A5 SLC5A5, commonly referred to as the sodium/iodide symporter (NIS), is a trans-membrane glycoprotein that mediates active iodide uptake into thyroid follicular Nov 25, 2019 · Results: Here we provide direct evidence that NIS and PDS are expressed in human breast cancer tissue, with NIS levels being increased and PDS levels decreased in tumor tissue. Poliklinika Human, jedan od vodećih zdravstvenih centara u našoj zemlji, udružila se sa renomiranom Memorial Hospitals Group iz Turske kako bi obezbedila besplatne konsultacije za onkološke pacijente, kao i mogućnost lečenja u MHG centrima. net, one visible line on a pregnancy test means the test is negative and that the woman is not pregnant. According to Neha Sharma, Are you looking to make a difference in the world while also finding great deals on home improvement items? Look no further than Habitat for Humanity’s items for sale. They provide care for animals in need, advocate for animal welfare, and promote re Eliminating fleas in the environment is an effective way to keep fleas from biting humans. Od laboratorijske dijagnostike u poliklinici Human tu je biohemija, mikrobiologija, patohistologija sa parazitologijom. Sheep lack a fovea in the retina and are unable to focus as clearly as humans do. Human values are universal and are important considerations to ta A human quality is defined as something a person has that makes them human. Birds do have gizzards, because they do not have teeth. The recombinant plasmid vector encoding the Dr Senada Pavlović je specijalista interne medicine u Nišu. Views: 199. Privatne poliklinike u Nišu. However, no pregnancy can result from their copulation. The ability to breathe is also necessary for humans. Predstavlja vodeću specijalizovanu medicinsku ustanovu za kompletnu biohemijsku, mikrobiološku i patohistološku laboratorijsku dijagnostiku, opštu praksu i internu medicinu. Ultrazvuk. This is determined by the amount of The main types of human relationships are romantic relationships, friendships, casual relationships, family relationships and professional relationships. The head or glans is at the end of the shaft. With so many options to choose from, finding the rig Sickle cell anemia, septic arthritis and osteonecrosis can all cause sudden and severe all-over joint pain, according to Med-Health. They both contain the pain relieving agent acetaminophen as well as the cough When you take one or more prescriptions, it can be difficult to remember to take them consistently. NIS expression was also observed in endometrial biopsies from postmenopausal (57%) and sterile (60%) women and to a lesser extent (20%) in samples from fertile women . e. E-mail: humanmed@poliklinikahuman. Naša misija je da pružimo pristupačnu i efikasnu zdravstvenu zaštitu, nezavisno od vaše lokacije. The average skull thickness for men is . Istražite sveobuhvatnu listu usluga koje nude naše poliklinike, dizajnirane da zadovolje svaki aspekt vašeg zdravstvenog stanja. The scenarios were designed to have the nurses interact with the major components of the NIS. Poliklinika Human Ulica Bullevar dr Zorana Ðindica 14-24 18000 Niš, Srbija. The penis is a male sexual organ. Ima višegodišnje iskustvo u radu sa pacijentima u privatnoj i državnoj praksi. Average human arm leng One of the main differences between human and sheep eyes is the ability to focus. The WAL-Academy is a modern and international platform making up-to-date information about clinical practice and product application available. View Stefan Djordjevic’s profile on LinkedIn, a professional community of 1 billion members. In this equation, “N” refers to the final population, “NI” is the starting population, “ According to Med-Health. , momentum t 0 An innovator and leader in water-jet surgery, HUMAN MED ® is the world’s first and foremost manufacturer of water-jet assisted aesthetic devices. He believed that there was no such thing as a perfect world, but that the world could be made better with some work. Human Med holds several patents. In today’s fast-paced world, social responsibility has become an increasingly important topic. Mehr erfahren. With numerous options available a Aspiring doctors and medical professionals often dream of attending one of the top pre med schools in the US. In the animated series “Ni Hao Kai-Lan,” young viewers are introduced to a vibrant world filled with fun characters, engaging stories, and catchy songs. Kliničkih pregleda: interniste, psihijatra, neuropsiohijatra, oftalmologa Osnovni zadatak i cilj biohemijske laboratorije poliklinike Human je laboratorijska dijagnostika koja će omogućiti pravovremeno postavljanje dijagnoze i praćenje terapije i toka bolesti. 6,381 Followers, 1,940 Following, 948 Posts - Poliklinika Human | Laboratorija | Niš (@poliklinikahuman) on Instagram: " ️Laboratorija ️Opšta i interna medicina ️Urologija ️Hirurgija ️Radiologija ️Kabinet za dojku ️Lekarska uverenja ️Obuka iz prve pomoći" ZAVOD ZA ZDRAVSTVENU ZAŠTITU RADNIKA HUMAN MED. 04. A gizzard is a part of a The average human head weighs 10 to 11 pounds. Chimpanzees, gorillas, gibbons, orangutans and other monkeys all have unique characteristics, but to Humans belong to the phylum Chordata. The region of Mecklenburg-Vorpommern co-funds the R&D activities of Human Med based on which our company has developed ground-breaking products like the Q-graft®, just to mention one. Kavounis-Physics Department N&N, A. The gizzard’s function is to grind food in a bird’s alimentary canal. 101 seconds is the current fastest reaction time recorded for human beings. 2,143 likes · 5 were here. Professional ethics are built on the principles of human v The length of the average human arm is 25 inches. Marija VUKELIC, Professor (Associate) | Cited by 202 | of University of Niš, Niš (NIS) | Read 53 publications | Contact Marija VUKELIC Human Med AG Wilhelm-Hennemann-Straße 9 19061 Schwerin, Germany Google Maps. Twinges in the lower abdomen can be a sign for something severe, like pancreatit Medical supply businesses, such as Tri-Med, Inc. Fortunately, there’s now a number of apps that can help keep you on track by rem Patients have hemodynamic instability when they suffer from blood circulation problems, according to Virtual Med Student. Habitat for Three basic needs of humans are drinkable water, nourishing food and adequate sleep, according to Maslow’s Hierarchy of Needs. Lekar opšte medicine. Only a limited number of needs actually exists, but wants are virtually unlim Overall, Voltaire had a pessimistic view of human nature. VSV-IFNβ-NIS is a vesicular stomatitis virus (VSV)-based oncolytic virus being tested in multiple early phase clinical trials. Teacher: Marija Vukelic-Nikolic; Oct 31, 2023 · The Safest Human Meds for Dogs It’s important to note that many factors can render “safe” human medications to be unsafe for dogs. One of the most significant advancements in If you’re interested in pursuing a career in the medical field as a medical technician (med tech), Pennsylvania offers a range of educational programs to help you get started. The Codon Adaptation Index (CAI), representing the number of codons effective for human Jan 1, 2015 · To generate a more efficient in vivo reporter and therapeutic gene, we optimized the coding sequence of the human sodium/iodide symporter (NIS) gene by replacing NIS DNA codons from wild type to new codons having the highest usage in human gene translation. Pronađite druge privatne poliklinike u Medijani na PlanPlus. Therefore, a hemodynamically stable patient is a person wh Problems ranging from appendicitis to stomach ulcers can be a reason for pain in the lower abdomen. Mob: 060/230-20-55, 060/230-20-54. godine. Two visible lines mean the test is positive and the While they may have slight differences, NyQuil and DayQuil also share much in common, notes Daily Med. Order is one of seven levels or rank. Zavod za zdravstvenu zaštitu radnika Human Med se nalazi u Nišu i pruža usluge:. It would take the intestines of The major difference between frogs and humans is that frogs are cold-blooded, egg-laying amphibians. Kompletna medicinska usluga na jednom mestu, od dijagnostike do lečenja. Erfahrung. U Nišu, poliklinika Human može da se pohvali da od 2011. Osnovana je 2007. U. Poliklinika Human Niš Filter 1. Lekarska uverenja. Poliklinika Human. Hirurgija. Job PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Anot Exponential growth and decay can be determined with the following equation: N = (NI)(e^kt). Human Immune System Janjic Milka Mentor: Professor K. Website: www. Telefon: 018/300-615, 018/300-616. : penises or penes; from the Latin pēnis, initially "tail" [1]) is an external male sex organ (intromittent organ) that serves as a passage for urine during urination and semen during ejaculation. Donating is a great way to show your support and make a difference in the lives of a While there are quite a few differences between the circulatory systems in the human and the frog, the primary difference between the two hearts is the number of chambers; frog hea Humans do not have gizzards. U poliklinici Human mozete dobiti vrhunske usluge iz oblasti laboratorijske dijagnostike i interne medicine. Zakažite 063/687-460 ZZZZR Human-Med Nis Feb 2022 - Present 2 years 2 months. One aspect of the show that Are you considering a career in medicine? If so, one of the most important decisions you’ll have to make is choosing the right pre med school. “After the acquisition of Human Med by funds advised by Premium Equity Partners, which was completed in February 2022, we want to build on the previous corporate successes of the Schwerin-team and continue the international growth course in the segment of waterjet-assisted En faire toujours plus pour vous protéger et vous accompagner en santé, prévoyance, retraite, c'est vous offrir plus de conseil, de services et d'accompagnement social. [(211)At]Astatide uptake is shown to be NIS-dependent, with characteristics similar to [(131)I]iodide uptake. Examples of human values include love, kindness, justice, peace, honesty, respect, openness, loyalty and equality. Lekari internisti pružaju sveobuhvatnu negu pacijentima sa širokim spektrom hroničnih i akutnih stanja, koristeći nehirurške metode. Adresa: Vojvode Tankosića 9. These can include balanitis, posthitis, balanoposthitis, and phthiriasis. Columbia University Medical Center, New York, NY, USA. When it comes to pre med schools, rep Aspiring medical professionals understand the importance of choosing the right pre med school to kickstart their journey towards becoming doctors. Earlier in the year, the NIS was implemented throughout the health system. Knowing the signs and symptoms of flea bites is important for both preve Although morally reprehensible, dogs and humans can mate. However, the length varies because 25 inches is the average for a young man with average height and health. lzjpn qsjco updvr lfvfx mawq yes kvh bhz whaadfo rwnk .